S(H)ARP is made possible by the institutions and companies that support our research with computational, financial and scientific resources. We are grateful to each of them.
USP Institute
The Institute of Biomedical Sciences (ICB-USP) is a teaching and research unit of the University of São Paulo and the place where our wet lab happens. Its Department of Microbiology has built decades of expertise in actinobacteria and in the discovery of bioactive molecules, a tradition our project follows closely. We are grateful to ICB for the bench space, the strain collections, and the researchers who guide our experiments.
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USP Institute
The Institute of Chemistry (IQ-USP) is a teaching and research unit of the University of São Paulo whose work in biochemistry and in science education informs how we approach our project. The questions we ask about enzyme function and metabolic cost come from that side of the university, as does much of our thinking about how to teach synthetic biology to people outside it. Our thanks to IQ for the guidance and for the space it opens for this kind of work.
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USP Office
The Office for Research and Innovation (PRPI) is one of the University of São Paulo's central bodies, responsible for fostering research across the university and for turning it into innovation. We rely on exactly that kind of institutional support to move an idea toward something real. We thank PRPI for backing research like ours.
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Funding
The São Paulo Research Foundation (FAPESP) is one of Brazil's principal scientific funding agencies, sustained by a share of the state's tax revenue and supporting research across every field of knowledge. Its long-term investment in basic microbiology and genomics in São Paulo is part of what makes a project like S(H)ARP possible in the first place, and we thank FAPESP for backing the infrastructure our work stands on.
iGEM Partnership
Ansa Biotechnologies manufactures synthetic DNA through a proprietary enzymatic process built on TdT-dNTP conjugates, avoiding the harsh chemistry of phosphoramidite synthesis and reaching sequences that legacy methods struggle to produce. That matters directly for us, since Streptomyces genomes are extremely GC-rich and their biosynthetic gene clusters are long and repetitive, precisely the constructs conventional synthesis declines. We thank Ansa for making this chemistry available to a student team.
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iGEM Partnership
Anthropic is an AI safety company and the developer of Claude, working to build AI systems that are reliable, interpretable, and steerable. As a team competing in the Software & AI Village, we care about the same question from the other side of the table, which is what it takes for a computational tool to earn a biologist's trust. Our thanks to Anthropic for supporting our work.
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iGEM Partnership
GenScript is a global biotechnology company offering gene and peptide synthesis, molecular cloning, and protein expression services to research groups worldwide. Their synthesis capability underpins the coding sequences in our modular parts library, including the Cas9, nCas9, and dCas9 variants at the center of our activation strategy. We are thankful for their support of iGEM teams year after year.
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iGEM Partnership
Integrated DNA Technologies (IDT) manufactures custom nucleic acids for research and clinical laboratories, including oligonucleotides, gBlocks gene fragments, and CRISPR reagents. Nearly every step of our wet lab passes through their products, from the primers that amplify our Golden Gate parts to the ERIC-PCR typing of soil isolates sent to us by the public. We thank IDT for keeping that pipeline moving.
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iGEM Partnership
MathWorks develops MATLAB and Simulink, the computational environment used across engineering and the quantitative sciences for numerical analysis, modeling, and simulation. Our dry lab relies on that kind of tooling to characterize promoter strength from fluorescence data and to model the metabolic cost of the pathways our software predicts. We appreciate MathWorks making these tools accessible to students.
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iGEM Partnership
SnapGene, now part of Dotmatics, is the molecular biology software most cloning labs live in day to day, used for planning assemblies, annotating features, and keeping a visual record of every construct. For a modular parts collection like ours, where type IIs sites must be tracked and removed across dozens of sequences, that documentation is a requirement rather than a convenience. We thank SnapGene for supporting our design work.
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iGEM Partnership
Twist Bioscience manufactures synthetic DNA on a silicon-based platform that miniaturizes the synthesis reaction, producing genes and oligonucleotide pools at a scale and cost that were out of reach a decade ago. Building the first standardized Golden Gate toolkit for Streptomyces means synthesizing many parts in parallel, and Twist is what makes that feasible on a student timeline. We are grateful for their sponsorship.
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